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Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

Antibody-drug conjugates (ADC), combining the specificity of tumor recognition by monoclonal antibodies (mAb) and the powerful cytotoxicity of anticancer drugs, are currently under growing interest and development. Here, we studied the potential of Chi-Tn, a mAb directed to a glyco-peptidic tumor-as...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncoimmunology
Main Authors: Sedlik, Christine, Heitzmann, Adèle, Viel, Sophie, Ait Sarkouh, Rafik, Batisse, Cornélie, Schmidt, Frédéric, De La Rochere, Philippe, Amzallag, Nathalie, Osinaga, Eduardo, Oppezzo, Pablo, Pritsch, Otto, Sastre-Garau, Xavier, Hubert, Pascale, Amigorena, Sebastian, Piaggio, Eliane
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006918/
https://ncbi.nlm.nih.gov/pubmed/27622021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1171434
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