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Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

Antibody-drug conjugates (ADC), combining the specificity of tumor recognition by monoclonal antibodies (mAb) and the powerful cytotoxicity of anticancer drugs, are currently under growing interest and development. Here, we studied the potential of Chi-Tn, a mAb directed to a glyco-peptidic tumor-as...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncoimmunology
Κύριοι συγγραφείς: Sedlik, Christine, Heitzmann, Adèle, Viel, Sophie, Ait Sarkouh, Rafik, Batisse, Cornélie, Schmidt, Frédéric, De La Rochere, Philippe, Amzallag, Nathalie, Osinaga, Eduardo, Oppezzo, Pablo, Pritsch, Otto, Sastre-Garau, Xavier, Hubert, Pascale, Amigorena, Sebastian, Piaggio, Eliane
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5006918/
https://ncbi.nlm.nih.gov/pubmed/27622021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1171434
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