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Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen
Antibody-drug conjugates (ADC), combining the specificity of tumor recognition by monoclonal antibodies (mAb) and the powerful cytotoxicity of anticancer drugs, are currently under growing interest and development. Here, we studied the potential of Chi-Tn, a mAb directed to a glyco-peptidic tumor-as...
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| 出版年: | Oncoimmunology |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5006918/ https://ncbi.nlm.nih.gov/pubmed/27622021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1171434 |
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