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Bile acid homeostasis in a Cyp7a1 & Cyp27a1 double knockout mouse model
Bile acids (BAs) are diverse molecules that are synthesized from cholesterol in the liver. The synthesis of BAs has traditionally been shown to occur via two pathways. Cholesterol 7α-hydroxylase (CYP7A1) performs the initial and rate-limiting step in the classical pathway and sterol 27-hydroxylase (...
שמור ב:
| הוצא לאור ב: | Hepatology |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7893641/ https://ncbi.nlm.nih.gov/pubmed/30864232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30612 |
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