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Bile acid homeostasis in a Cyp7a1 & Cyp27a1 double knockout mouse model
Bile acids (BAs) are diverse molecules that are synthesized from cholesterol in the liver. The synthesis of BAs has traditionally been shown to occur via two pathways. Cholesterol 7α-hydroxylase (CYP7A1) performs the initial and rate-limiting step in the classical pathway and sterol 27-hydroxylase (...
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| Publicado no: | Hepatology |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7893641/ https://ncbi.nlm.nih.gov/pubmed/30864232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30612 |
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