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27-Hydroxycholesterol induces macrophage gene expression via LXR-dependent and -independent mechanisms
27-Hydroxycholesterol (27OHChol) exhibits agonistic activity for liver X receptors (LXRs). To determine roles of the LXR agonistic activity in macrophage gene expression, we investigated the effects of LXR inhibition on the 27OHChol-induced genes. Treatment of human THP-1 cells with GSK 2033, a pote...
Tallennettuna:
| Julkaisussa: | Korean J Physiol Pharmacol |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The Korean Physiological Society and The Korean Society of Pharmacology
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7893494/ https://ncbi.nlm.nih.gov/pubmed/33602881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2021.25.2.111 |
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