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7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptor

We investigated effects of 7-oxygenated cholesterol derivatives present in atherosclerotic lesions, 7α-hydroxycholesterol (7αOHChol), 7β-hydroxycholesterol (7βOHChol), and 7-ketocholesterol (7K), on IL-8 expression. Transcript levels of IL-8 and secretion of its corresponding gene product by monocyt...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cho, Hyok-rae, Son, Yonghae, Kim, Sun-Mi, Kim, Bo-Young, Eo, Seong-Kug, Park, Young Chul, Kim, Koanhoi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360241/
https://ncbi.nlm.nih.gov/pubmed/28323848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173749
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