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Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma

Background: O6-methylguanine-DNA methyltransferase (MGMT) methylation status affects tumor chemo-resistance and the prognosis of glioblastoma (GBM) patients. We aimed to investigate the role of MGMT methylation in the regulation of GBM immunophenotype and discover an effective biomarker to improve p...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zhao, Liang, Zhang, Jiayue, Xuan, Shurui, Liu, Zhiyuan, Wang, Yu, Zhao, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892978/
https://ncbi.nlm.nih.gov/pubmed/33614641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.600506
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