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Molecular and Clinicopathological Characterization of a Prognostic Immune Gene Signature Associated With MGMT Methylation in Glioblastoma

Background: O6-methylguanine-DNA methyltransferase (MGMT) methylation status affects tumor chemo-resistance and the prognosis of glioblastoma (GBM) patients. We aimed to investigate the role of MGMT methylation in the regulation of GBM immunophenotype and discover an effective biomarker to improve p...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Zhao, Liang, Zhang, Jiayue, Xuan, Shurui, Liu, Zhiyuan, Wang, Yu, Zhao, Peng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892978/
https://ncbi.nlm.nih.gov/pubmed/33614641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.600506
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