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PANDAA intentionally violates conventional qPCR design to enable durable, mismatch-agnostic detection of highly polymorphic pathogens

Sensitive and reproducible diagnostics are fundamental to containing the spread of existing and emerging pathogens. Despite the reliance of clinical virology on qPCR, technical challenges persist that compromise their reliability for sustainable epidemic containment as sequence instability in probe-...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: MacLeod, Iain J., Rowley, Christopher F., Essex, M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892852/
https://ncbi.nlm.nih.gov/pubmed/33603155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01751-9
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