Ultrasensitive Detection of Minor Drug-Resistant Variants for HIV After Nevirapine Exposure Using Allele-Specific PCR: Clinical Significance

HIV-1 drug resistance mutations have been detected at low frequencies after single-dose nevirapine (sdNVP) for prevention of mother-to-child transmission (PMTCT). We investigated the relationship between these “minor variant” NVP-resistant viruses and clinical outcome with NVP-containing antiretrovi...

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Detalhes bibliográficos
Main Authors: Rowley, Christopher F., Boutwell, Christian L., Lee, Esther J., MacLeod, Iain J., Ribaudo, Heather J., Essex, M., Lockman, Shahin
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Preclinical Studies/Drug Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864062/
https://ncbi.nlm.nih.gov/pubmed/20334564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2009.0082
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