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Improvement in allele-specific PCR assay with the use of polymorphism-specific primers for the analysis of minor variant drug resistance in HIV-1 subtype C

In recent years, highly sensitive assays have been developed that detect HIV-1 drug resistance mutations when present at less than 1% of the viral population. These assays are powerful tools when attempting to determine the clinical implications of these low level resistant virions after the adminis...

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Autores principales: Rowley, Christopher F., Boutwell, Christian L., Lockman, Shahin, Essex, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927209/
https://ncbi.nlm.nih.gov/pubmed/18295909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2008.01.005
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