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Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens

A major proportion of allergic reactions to hazelnuts (Corylus avellana) are caused by immunologic cross-reactivity of IgE antibodies to pathogenesis-related class 10 (PR-10) proteins. Intriguingly, the four known isoforms of the hazelnut PR-10 allergen Cor a 1, denoted as Cor a 1.0401–Cor a 1.0404,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Führer, Sebastian, Kamenik, Anna S., Zeindl, Ricarda, Nothegger, Bettina, Hofer, Florian, Reider, Norbert, Liedl, Klaus R., Tollinger, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892832/
https://ncbi.nlm.nih.gov/pubmed/33603065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83705-z
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