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RAS Function in Cancer Cells: Translating Membrane Biology and Biochemistry into New Therapeutics
The three human RAS proteins are mutated and constitutively activated in ~20% of cancers leading to cell growth and proliferation. For the past 3 decades, many attempts have been made to inhibit these proteins with little success. Recently; however, multiple methods have emerged to inhibit KRAS, the...
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| Udgivet i: | Biochem J |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7891675/ https://ncbi.nlm.nih.gov/pubmed/32797215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190839 |
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