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Opportunities and challenges for antisense oligonucleotide therapies
Antisense oligonucleotide (AON) therapies involve short strands of modified nucleotides that target RNA in a sequence‐specific manner, inducing targeted protein knockdown or restoration. Currently, 10 AON therapies have been approved in the United States and Europe. Nucleotides are chemically modifi...
Shranjeno v:
| izdano v: | J Inherit Metab Dis |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley & Sons, Inc.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7891411/ https://ncbi.nlm.nih.gov/pubmed/32391605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12251 |
| Oznake: |
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