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Opportunities and challenges for antisense oligonucleotide therapies
Antisense oligonucleotide (AON) therapies involve short strands of modified nucleotides that target RNA in a sequence‐specific manner, inducing targeted protein knockdown or restoration. Currently, 10 AON therapies have been approved in the United States and Europe. Nucleotides are chemically modifi...
Tallennettuna:
| Julkaisussa: | J Inherit Metab Dis |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley & Sons, Inc.
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7891411/ https://ncbi.nlm.nih.gov/pubmed/32391605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12251 |
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