Delivery of oligonucleotide‐based therapeutics: challenges and opportunities

Nucleic acid‐based therapeutics that regulate gene expression have been developed towards clinical use at a steady pace for several decades, but in recent years the field has been accelerating. To date, there are 11 marketed products based on antisense oligonucleotides, aptamers and small interferin...

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發表在:EMBO Mol Med
Main Authors: Hammond, Suzan M, Aartsma‐Rus, Annemieke, Alves, Sandra, Borgos, Sven E, Buijsen, Ronald A M, Collin, Rob W J, Covello, Giuseppina, Denti, Michela A, Desviat, Lourdes R, Echevarría, Lucía, Foged, Camilla, Gaina, Gisela, Garanto, Alejandro, Goyenvalle, Aurelie T, Guzowska, Magdalena, Holodnuka, Irina, Jones, David R, Krause, Sabine, Lehto, Taavi, Montolio, Marisol, Van Roon‐Mom, Willeke, Arechavala‐Gomeza, Virginia
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033518/
https://ncbi.nlm.nih.gov/pubmed/33821570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202013243
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