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Splicing modulation therapy in the treatment of genetic diseases

Antisense-mediated splicing modulation is a tool that can be exploited in several ways to provide a potential therapy for rare genetic diseases. This approach is currently being tested in clinical trials for Duchenne muscular dystrophy and spinal muscular atrophy. The present review outlines the ver...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Arechavala-Gomeza, Virginia, Khoo, Bernard, Aartsma-Rus, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259397/
https://ncbi.nlm.nih.gov/pubmed/25506237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S71506
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