Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity

Glycyl‐tRNA synthetase 1 (GARS1), a cytosolic enzyme secreted from macrophages, promotes apoptosis in cancer cells. However, the mechanism underlying GARS1 secretion has not been elucidated. Here, we report that GARS1 is secreted through unique extracellular vesicles (EVs) with a hydrodynamic diamet...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Goughnour, Peter C., Park, Min Chul, Kim, Sang Bum, Jun, Sangmi, Yang, Won Suk, Chae, Sehyun, Cho, Seongmin, Song, Chihong, Lee, Ji‐Hyun, Hyun, Jae Kyung, Kim, Byung Gyu, Hwang, Daehee, Jung, Hyun Suk, Gho, Yong Song, Kim, Sunghoon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890555/
https://ncbi.nlm.nih.gov/pubmed/33708357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12029
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