Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells

Aminoacyl-tRNA synthetases (ARSs), enzymes that normally control protein synthesis, can be secreted and have different activities in the extracellular space, but the mechanism of their secretion is not understood. This study describes the secretion route of the ARS lysyl-tRNA synthetase (KRS) and ho...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Kim, Sang Bum, Kim, Hye Rim, Park, Min Chul, Cho, Seongmin, Goughnour, Peter C., Han, Daeyoung, Yoon, Ina, Kim, YounHa, Kang, Taehee, Song, Eunjoo, Kim, Pilhan, Choi, Hyosun, Mun, Ji Young, Song, Chihong, Lee, Sangmin, Jung, Hyun Suk, Kim, Sunghoon
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496609/
https://ncbi.nlm.nih.gov/pubmed/28611052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201605118
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