Impaired NEPHRIN localization in kidney organoids derived from nephrotic patient iPS cells

Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. We previously reported NEPHRIN and SD abnormalities in the podocytes of kidney organoids generated from patient-derived induced plur...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ohmori, Tomoko, De, Shankhajit, Tanigawa, Shunsuke, Miike, Koichiro, Islam, Mazharul, Soga, Minami, Era, Takumi, Shiona, Shinichi, Nakanishi, Koichi, Nakazato, Hitoshi, Nishinakamura, Ryuichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890052/
https://ncbi.nlm.nih.gov/pubmed/33597637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83501-9
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