Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome, resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. However, methods for SD reconstitution have been unavailable, thereby limiting studies in the field. In the present study, we establ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Tanigawa, Shunsuke, Islam, Mazharul, Sharmin, Sazia, Naganuma, Hidekazu, Yoshimura, Yasuhiro, Haque, Fahim, Era, Takumi, Nakazato, Hitoshi, Nakanishi, Koichi, Sakuma, Tetsushi, Yamamoto, Takashi, Kurihara, Hidetake, Taguchi, Atsuhiro, Nishinakamura, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135868/
https://ncbi.nlm.nih.gov/pubmed/30174315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.08.003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados