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Stability and folding pathways of tetra-nucleosome from six-dimensional free energy surface

The three-dimensional organization of chromatin is expected to play critical roles in regulating genome functions. High-resolution characterization of its structure and dynamics could improve our understanding of gene regulation mechanisms but has remained challenging. Using a near-atomistic model t...

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Publicat a:Nat Commun
Autors principals: Ding, Xinqiang, Lin, Xingcheng, Zhang, Bin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889939/
https://ncbi.nlm.nih.gov/pubmed/33597548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21377-z
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