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Hidden complexity of free energy surfaces for peptide (protein) folding

An understanding of the thermodynamics and kinetics of protein folding requires a knowledge of the free energy surface governing the motion of the polypeptide chain. Because of the many degrees of freedom involved, surfaces projected on only one or two progress variables are generally used in descri...

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Autori principali: Krivov, Sergei V., Karplus, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC522040/
https://ncbi.nlm.nih.gov/pubmed/15466711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406234101
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