Ferroportin-Dependent Iron Homeostasis Protects against Oxidative Stress-Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo

Ferroptosis is a specialized form of regulated cell death that is charactered by iron-dependent lethal lipid peroxidation, a process associated with multiple diseases. However, its role in the pathogenesis of intervertebral disc degeneration (IVDD) is rarely investigated. This study is aimed at inve...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Lu, Saideng, Song, Yu, Luo, Rongjin, Li, Shuai, Li, Gaocai, Wang, Kun, Liao, Zhiwei, Wang, Bingjin, Ke, Wencan, Xiang, Qian, Chen, Chao, Wu, Xinghuo, Zhang, Yukun, Ling, Li, Yang, Cao
Format: Artigo
Language:Inglês
Published: Hindawi 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889334/
https://ncbi.nlm.nih.gov/pubmed/33628376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6670497
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