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Observation of the Imidazole-Imidazolium Hydrogen Bonds Responsible for Selective Proton Conductance in the Influenza A M2 Channel
The integral membrane M2 protein is a 97-residue membrane protein that assembles as a tetramer to conduct protons at a slow rate (10(2)−10(3)/s) when activated by low pH. The proton conductance mechanism has been extensively debated in the literature, but it is accepted that the proton conductance i...
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| Опубликовано в: : | J Am Chem Soc |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7889243/ https://ncbi.nlm.nih.gov/pubmed/31970982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09985 |
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