USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial–mesenchymal transition of TNBC cells via stabilizing TAK1

Triple-negative breast cancer (TNBC) is the most aggressive histological subtype of breast cancer and is characterized by poor outcomes and a lack of specific-targeted therapies. Transforming growth factor-β (TGF-β) acts as the key cytokine in the epithelial–mesenchymal transition (EMT) and the meta...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Han, Dianwen, Wang, Lijuan, Chen, Bing, Zhao, Wenjing, Liang, Yiran, Li, Yaming, Zhang, Hanwen, Liu, Ying, Wang, Xiaolong, Chen, Tong, Li, Chen, Song, Xiaojin, Luo, Dan, Li, Zheng, Yang, Qifeng
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889205/
https://ncbi.nlm.nih.gov/pubmed/33461373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2021.1874695
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