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CircEIF3H-IGF2BP2-HuR scaffold complex promotes TNBC progression via stabilizing HSPD1/RBM8A/G3BP1 mRNA

Abstract Triple-negative breast cancer (TNBC) is a molecular subtype with an unfavorable prognosis, and metastasis is the main reason for the failure of clinical treatment. However, the expression profile and regulatory function of circRNAs in TNBC progression are not fully understood. Herein, we pe...

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Detalhes bibliográficos
Main Authors: Xiaojin Song, Bing Chen, Yiran Liang, Yaming Li, Hanwen Zhang, Dianwen Han, Yajie Wang, Fangzhou Ye, Lijuan Wang, Wenjing Zhao, Qifeng Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-05-01
Colecção:Cell Death Discovery
Acesso em linha:https://doi.org/10.1038/s41420-022-01055-9
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