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Activin A backs-up TGF-ß to promote regulatory T cells

The mechanisms accountable for the infiltration of regulatory T cells into an irradiated tumor remain elusive. In our recent study, we demonstrate that activin A promotes regulatory T cells in tumors, and impairs anti-tumor immune responses induced by radiotherapy and TGF-β blockade. Dual blockade o...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: De Martino, Mara, Daviaud, Camille, Vanpouille-Box, Claire
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889161/
https://ncbi.nlm.nih.gov/pubmed/33628624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1883288
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