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DDRE-26. THE IMMUNO-METABOLIC ENZYME FASN PREVENTS CANCER-CELL INTRINSIC TYPE I INTERFERON RESPONSES IN GLIOBLASTOMA

Glioblastoma (GBM) is a devastating primary brain cancer with a median survival of 11–15 months. Radiation therapy (RT), the standard of care for GBM, can generate type I interferon responses (IFN-I) to jumpstart antitumor immunity. However, these effects are sometimes mitigated by inhibitory mechan...

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Detalles Bibliográficos
Publicado en:Neurooncol Adv
Autores principales: De Martino, Mara, Daviaud, Camille, Vanpouille-Box, Claire
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7992208/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdab024.048
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