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TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy
Mislocalization of the TAR DNA-binding protein 43 (TDP-43; encoded by TARDBP) from the nucleus to the cytoplasm is a common feature of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The downstream in vivo cellular effects of thi...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7888715/ https://ncbi.nlm.nih.gov/pubmed/33408125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.047548 |
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