BRG1 knockdown inhibits proliferation through multiple cellular pathways in prostate cancer

BACKGROUND: BRG1 (encoded by SMARCA4) is a catalytic component of the SWI/SNF chromatin remodelling complex, with key roles in modulating DNA accessibility. Dysregulation of BRG1 is observed, but functionally uncharacterised, in a wide range of malignancies. We have probed the functions of BRG1 on a...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Giles, Katherine A., Gould, Cathryn M., Achinger-Kawecka, Joanna, Page, Scott G., Kafer, Georgia R., Rogers, Samuel, Luu, Phuc-Loi, Cesare, Anthony J., Clark, Susan J., Taberlay, Phillippa C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888175/
https://ncbi.nlm.nih.gov/pubmed/33596994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01023-7
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