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Random Forest Model Prediction of Compound Oral Exposure in the Mouse

[Image: see text] An early hurdle in the optimization of small-molecule chemical probes and drug discovery entities is the attainment of sufficient exposure in the mouse via oral administration of the compound. While computational approaches have attempted to predict molecular properties related to...

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Detalhes bibliográficos
Publicado no:ACS Pharmacol Transl Sci
Main Authors: Mughal, Haseeb, Wang, Han, Zimmerman, Matthew, Paradis, Marc d., Freundlich, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887840/
https://ncbi.nlm.nih.gov/pubmed/33615183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00197
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