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Random Forest Model Prediction of Compound Oral Exposure in the Mouse

[Image: see text] An early hurdle in the optimization of small-molecule chemical probes and drug discovery entities is the attainment of sufficient exposure in the mouse via oral administration of the compound. While computational approaches have attempted to predict molecular properties related to...

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Publicat a:ACS Pharmacol Transl Sci
Autors principals: Mughal, Haseeb, Wang, Han, Zimmerman, Matthew, Paradis, Marc d., Freundlich, Joel S.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2021
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887840/
https://ncbi.nlm.nih.gov/pubmed/33615183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00197
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