LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells

The production of blood cells during steady-state and increased demand depends on the regulation of hematopoietic stem cell (HSC) self-renewal and differentiation. Similarly, the balance between self-renewal and differentiation of leukemia stem cells (LSCs) is crucial in the pathogenesis of leukemia...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Höpner, S. S., Raykova, Ana, Radpour, R., Amrein, M. A., Koller, D., Baerlocher, G. M., Riether, C., Ochsenbein, A. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887212/
https://ncbi.nlm.nih.gov/pubmed/33594067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21317-x
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