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Retardation of Folding Rates of Substrate Proteins in the Nanocage of GroEL
The Escherichia coli ATP-consuming chaperonin machinery, a complex between GroEL and GroES, has evolved to facilitate folding of substrate proteins (SPs) that cannot do so spontaneously. A series of kinetic experiments show that the SPs are encapsulated in the GroEL/ES nanocage for a short duration....
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887066/ https://ncbi.nlm.nih.gov/pubmed/33464880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00903 |
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