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GroEL actively stimulates folding of the endogenous substrate protein PepQ

Many essential proteins cannot fold without help from chaperonins, like the GroELS system of Escherichia coli. How chaperonins accelerate protein folding remains controversial. Here we test key predictions of both passive and active models of GroELS-stimulated folding, using the endogenous E. coli m...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Weaver, Jeremy, Jiang, Mengqiu, Roth, Andrew, Puchalla, Jason, Zhang, Junjie, Rye, Hays S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497066/
https://ncbi.nlm.nih.gov/pubmed/28665408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15934
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