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Effects of Interactions with the GroEL Cavity on Protein Folding Rates

Encapsulation of proteins in chaperonins is an important mechanism by which the cell prevents the accumulation of misfolded species in the cytosol. However, results from theory and simulation for repulsive cavities appear to be inconsistent with recent experimental results showing, if anything, a sl...

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Bibliografske podrobnosti
Main Authors: Sirur, Anshul, Best, Robert B.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870810/
https://ncbi.nlm.nih.gov/pubmed/23473493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.034
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