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Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins

The membrane insertase YidC inserts newly synthesized proteins by its hydrophobic slide consisting of the two transmembrane (TM) segments TM3 and TM5. Mutations in this part of the protein affect the insertion of the client proteins. We show here that a quintuple mutation, termed YidC-5S, inhibits t...

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書目詳細資料
發表在:Sci Rep
Main Authors: Steudle, Anja, Spann, Dirk, Pross, Eva, Shanmugam, Sri Karthika, Dalbey, Ross E., Kuhn, Andreas
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886851/
https://ncbi.nlm.nih.gov/pubmed/33594158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83224-x
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