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YidC and SecYEG form a heterotetrameric protein translocation channel

The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics. The SecYE...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sachelaru, Ilie, Winter, Lukas, Knyazev, Denis G., Zimmermann, Mirjam, Vogt, Andreas, Kuttner, Roland, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Koch, Hans-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427846/
https://ncbi.nlm.nih.gov/pubmed/28273911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00109-8
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