YidC and SecYEG form a heterotetrameric protein translocation channel

The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics. The SecYE...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sachelaru, Ilie, Winter, Lukas, Knyazev, Denis G., Zimmermann, Mirjam, Vogt, Andreas, Kuttner, Roland, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Koch, Hans-Georg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427846/
https://ncbi.nlm.nih.gov/pubmed/28273911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00109-8
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