YidC and SecYEG form a heterotetrameric protein translocation channel

The heterotrimeric SecYEG complex cooperates with YidC to facilitate membrane protein insertion by an unknown mechanism. Here we show that YidC contacts the interior of the SecY channel resulting in a ligand-activated and voltage-dependent complex with distinct ion channel characteristics. The SecYE...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Sachelaru, Ilie, Winter, Lukas, Knyazev, Denis G., Zimmermann, Mirjam, Vogt, Andreas, Kuttner, Roland, Ollinger, Nicole, Siligan, Christine, Pohl, Peter, Koch, Hans-Georg
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427846/
https://ncbi.nlm.nih.gov/pubmed/28273911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00109-8
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