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Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins

The membrane insertase YidC inserts newly synthesized proteins by its hydrophobic slide consisting of the two transmembrane (TM) segments TM3 and TM5. Mutations in this part of the protein affect the insertion of the client proteins. We show here that a quintuple mutation, termed YidC-5S, inhibits t...

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Foilsithe in:Sci Rep
Main Authors: Steudle, Anja, Spann, Dirk, Pross, Eva, Shanmugam, Sri Karthika, Dalbey, Ross E., Kuhn, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886851/
https://ncbi.nlm.nih.gov/pubmed/33594158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83224-x
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