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Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins

The membrane insertase YidC inserts newly synthesized proteins by its hydrophobic slide consisting of the two transmembrane (TM) segments TM3 and TM5. Mutations in this part of the protein affect the insertion of the client proteins. We show here that a quintuple mutation, termed YidC-5S, inhibits t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Steudle, Anja, Spann, Dirk, Pross, Eva, Shanmugam, Sri Karthika, Dalbey, Ross E., Kuhn, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886851/
https://ncbi.nlm.nih.gov/pubmed/33594158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83224-x
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