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Molecular communication of the membrane insertase YidC with translocase SecYEG affects client proteins
The membrane insertase YidC inserts newly synthesized proteins by its hydrophobic slide consisting of the two transmembrane (TM) segments TM3 and TM5. Mutations in this part of the protein affect the insertion of the client proteins. We show here that a quintuple mutation, termed YidC-5S, inhibits t...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7886851/ https://ncbi.nlm.nih.gov/pubmed/33594158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83224-x |
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