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Phospho-Form Specific Substrates of Protein Kinase B (AKT1)
Protein kinase B (AKT1) is hyper-activated in diverse human tumors. AKT1 is activated by phosphorylation at two key regulatory sites, Thr308 and Ser473. Active AKT1 phosphorylates many, perhaps hundreds, of downstream cellular targets in the cytosol and nucleus. AKT1 is well-known for phosphorylatin...
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| Publié dans: | Front Bioeng Biotechnol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7886700/ https://ncbi.nlm.nih.gov/pubmed/33614606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.619252 |
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