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Structural Insights into Anthranilate Priming during Type II Polyketide Biosynthesis

The incorporation of nonacetate starter units during type II polyketide biosynthesis helps diversify natural products. Currently, there are few enzymatic strategies for the incorporation of nonacetate starter units in type II polyketide synthase (PKS) pathways. Here we report the crystal structure o...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Jackson, David R., Tu, Stephanie S., Nguyen, MyChi, Barajas, Jesus F., Schaub, Andrew J., Krug, Daniel, Pistorius, Dominik, Luo, Ray, Müller, Rolf, Tsai, Shiou-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886370/
https://ncbi.nlm.nih.gov/pubmed/26473393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00500
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