A pipeline to evaluate inhibitors of the Pseudomonas aeruginosa exotoxin U

Pseudomonas aeruginosa has recently been highlighted by the World Health Organisation (WHO) as a major threat with high priority for the development of new therapies. In severe P. aeruginosa infections, the phospholipase activity of the type 3 secretion system toxin, ExoU, induces lysis of target ho...

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Dades bibliogràfiques
Publicat a:Biochem J
Autors principals: Foulkes, Daniel M., McLean, Keri, Zheng, Yalin, Sarsby, Joscelyn, Haneef, Atikah S., Fernig, David G., Winstanley, Craig, Berry, Neil, Kaye, Stephen B.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2021
Matèries:
Enzymology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886320/
https://ncbi.nlm.nih.gov/pubmed/33459338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200780
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