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Pseudomonas aeruginosa Toxin ExoU as a Therapeutic Target in the Treatment of Bacterial Infections

The opportunistic pathogen Pseudomonas aeruginosa employs the type III secretion system (T3SS) and four effector proteins, ExoS, ExoT, ExoU, and ExoY, to disrupt cellular physiology and subvert the host’s innate immune response. Of the effector proteins delivered by the T3SS, ExoU is the most toxic....

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Detalhes bibliográficos
Publicado no:Microorganisms
Main Authors: Foulkes, Daniel M., McLean, Keri, Haneef, Atikah S., Fernig, David G., Winstanley, Craig, Berry, Neil, Kaye, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955817/
https://ncbi.nlm.nih.gov/pubmed/31888268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/microorganisms7120707
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