SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK-3β signaling pathway in esophageal squamous cell carcinoma

The human SOX2 gene was recently identified as a novel major oncogene, recurrently amplified and overexpressed in esophageal squamous cell carcinoma (ESCC). However, the role and molecular mechanism of SOX2 in the carcinogenesis of ESCC remain to be elucidated. The present study investigated the eff...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Terasaki, Kei, Gen, Yasuyuki, Iwai, Naoto, Soda, Tomohiro, Kitaichi, Tomoko, Dohi, Osamu, Taketani, Hiroyoshi, Seko, Yuya, Umemura, Atsushi, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito, Yasui, Kohichiroh
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2021
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885160/
https://ncbi.nlm.nih.gov/pubmed/33717266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12530
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