SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK-3β signaling pathway in esophageal squamous cell carcinoma

The human SOX2 gene was recently identified as a novel major oncogene, recurrently amplified and overexpressed in esophageal squamous cell carcinoma (ESCC). However, the role and molecular mechanism of SOX2 in the carcinogenesis of ESCC remain to be elucidated. The present study investigated the eff...

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Pubblicato in:Oncol Lett
Autori principali: Terasaki, Kei, Gen, Yasuyuki, Iwai, Naoto, Soda, Tomohiro, Kitaichi, Tomoko, Dohi, Osamu, Taketani, Hiroyoshi, Seko, Yuya, Umemura, Atsushi, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito, Yasui, Kohichiroh
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885160/
https://ncbi.nlm.nih.gov/pubmed/33717266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12530
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