SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK-3β signaling pathway in esophageal squamous cell carcinoma

The human SOX2 gene was recently identified as a novel major oncogene, recurrently amplified and overexpressed in esophageal squamous cell carcinoma (ESCC). However, the role and molecular mechanism of SOX2 in the carcinogenesis of ESCC remain to be elucidated. The present study investigated the eff...

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Publicado no:Oncol Lett
Main Authors: Terasaki, Kei, Gen, Yasuyuki, Iwai, Naoto, Soda, Tomohiro, Kitaichi, Tomoko, Dohi, Osamu, Taketani, Hiroyoshi, Seko, Yuya, Umemura, Atsushi, Nishikawa, Taichiro, Yamaguchi, Kanji, Moriguchi, Michihisa, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito, Yasui, Kohichiroh
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885160/
https://ncbi.nlm.nih.gov/pubmed/33717266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12530
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