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Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver
All-trans-retinoic acid (atRA) is a critical endogenous signaling molecule. atRA is predominantly synthesized from retinaldehyde by aldehyde dehydrogenase 1A1 (ALDH1A1), but aldehyde oxidase (AOX) may also contribute to atRA biosynthesis. The goal of this study was to test the hypothesis that AOX co...
Gespeichert in:
| Veröffentlicht in: | Drug Metab Dispos |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885020/ https://ncbi.nlm.nih.gov/pubmed/33355213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.120.000296 |
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