STIM2 Mediates Excessive Store-Operated Calcium Entry in Patient-Specific iPSC-Derived Neurons Modeling a Juvenile Form of Huntington's Disease

Huntington's disease (HD) is a severe autosomal-dominant neurodegenerative disorder caused by a mutation within a gene, encoding huntingtin protein. Here we have used the induced pluripotent stem cell technology to produce patient-specific terminally differentiated GABA-ergic medium spiny neuro...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Cell Dev Biol
Päätekijät: Vigont, Vladimir A., Grekhnev, Dmitriy A., Lebedeva, Olga S., Gusev, Konstantin O., Volovikov, Egor A., Skopin, Anton Yu., Bogomazova, Alexandra N., Shuvalova, Lilia D., Zubkova, Olga A., Khomyakova, Ekaterina A., Glushankova, Lyubov N., Klyushnikov, Sergey A., Illarioshkin, Sergey N., Lagarkova, Maria A., Kaznacheyeva, Elena V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021
Aiheet:
Cell and Developmental Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884642/
https://ncbi.nlm.nih.gov/pubmed/33604336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.625231
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