Caricamento...
4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling
Clinical response to chimeric antigen receptor (CAR) T cell therapy is correlated with CAR T cell persistence, especially for CAR T cells that target CD19(+) hematologic malignancies. 4-1BB–costimulated CAR (BBζ) T cells exhibit longer persistence after adoptive transfer than do CD28-costimulated CA...
Salvato in:
| Pubblicato in: | Sci Signal |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7883633/ https://ncbi.nlm.nih.gov/pubmed/32234960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay8248 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|