Á lódáil...

4-1BB costimulation promotes CAR T cell survival through noncanonical NF-κB signaling

Clinical response to chimeric antigen receptor (CAR) T cell therapy is correlated with CAR T cell persistence, especially for CAR T cells that target CD19(+) hematologic malignancies. 4-1BB–costimulated CAR (BBζ) T cells exhibit longer persistence after adoptive transfer than do CD28-costimulated CA...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Sci Signal
Main Authors: Philipson, Benjamin I., O’Connor, Roddy S., May, Michael J., June, Carl H., Albelda, Steven M., Milone, Michael C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883633/
https://ncbi.nlm.nih.gov/pubmed/32234960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aay8248
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!