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Noncanonical NF-κB Signaling Is Limited by Classical NF-κB Activity

Precise regulation of nuclear factor κB (NF-κB) signaling is crucial for normal immune responses, and defective NF-κB activity underlies a range of immunodeficiencies. NF-κB is activated through two signaling cascades: the classical and noncanonical pathways. The classical pathway requires inhibitor...

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Détails bibliographiques
Auteurs principaux: Gray, Carolyn M., Remouchamps, Caroline, McCorkell, Kelly A., Solt, Laura A., Dejardin, Emmanuel, Orange, Jordan S., May, Michael J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960999/
https://ncbi.nlm.nih.gov/pubmed/24497610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004557
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